Modeling Dependencies in Protein-DNA Binding Sites:
Analysis of Aligned Data

To test whether dependencies can be found in DNA binding sites, we have extracted aligned sites from the TRANSFAC database, version 6.2. We have used TRANSFAC's original alignment, and built 95 datasets for proteins having at least 20 known binding sites. For each group, we've performed a 10-fold cross validation test, learning a model on 90% of the sites, and then calculating the log-likelihood of the rest 10%.

The following table summarizes this data, and shows the differences in the average log-likelihood per instance on the test data.

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

1

F$ABAA_01

22 samples

-27.67
1.0e+00
(pic) (net)

-27.78
8.2e-01
(pic) (net)

-27.83
7.1e-01
(pic) (net) Clust=( 0.32 0.68 )

-28.92
1.0e-00
(pic) (net) Clust=( 0.65 0.35 )

2

F$GCN4_01

43 samples

-27.32
1.0e+00
(pic) (net)

-27.33
9.6e-01
(pic) (net)

-27.82
1.0e-00
(pic) (net) Clust=( 0.26 0.74 )

-27.79
9.9e-01
(pic) (net) Clust=( 0.30 0.70 )

3

F$MCM1_01

23 samples

-21.11
1.0e+00
(pic) (net)

-21.11
1.0e+00
(pic) (net)

-21.23
7.5e-01
(pic) (net) Clust=( 0.70 0.30 )

-21.77
9.5e-01
(pic) (net) Clust=( 0.34 0.66 )

4

I$CF1_02

38 samples

-5.57
1.0e+00
(pic) (net)

-5.56
4.7e-01
(pic) (net)

-5.29
3.3e-03
(pic) (net) Clust=( 0.94 0.06 )

-5.13
3.5e-05
(pic) (net) Clust=( 0.06 0.94 )

5

I$CF2II_01

80 samples

-7.78
1.0e+00
(pic) (net)

-7.78
1.0e+00
(pic) (net)

-7.60
5.9e-02
(pic) (net) Clust=( 0.94 0.06 )

-7.53
3.1e-02
(pic) (net) Clust=( 0.94 0.06 )

6

I$DL_01

22 samples

-9.07
1.0e+00
(pic) (net)

-9.07
1.0e+00
(pic) (net)

-8.74
4.2e-03
(pic) (net) Clust=( 0.09 0.91 )

-8.82
4.4e-02
(pic) (net) Clust=( 0.09 0.91 )

7

I$DRI_01

42 samples

-11.85
1.0e+00
(pic) (net)

-11.85
1.0e+00
(pic) (net)

-11.81
4.0e-01
(pic) (net) Clust=( 0.72 0.28 )

-11.72
2.6e-01
(pic) (net) Clust=( 0.70 0.30 )

8

I$OVO_01

21 samples

-22.81
1.0e+00
(pic) (net)

-22.81
1.0e+00
(pic) (net)

-23.36
9.8e-01
(pic) (net) Clust=( 0.56 0.44 )

-23.35
9.9e-01
(pic) (net) Clust=( 0.55 0.45 )

9

I$SN_01

40 samples

-11.56
1.0e+00
(pic) (net)

-11.47
1.7e-02
(pic) (net)

-11.45
1.2e-01
(pic) (net) Clust=( 0.08 0.92 )

-11.51
3.7e-01
(pic) (net) Clust=( 0.08 0.92 )

10

I$UBX_01

88 samples

-16.41
1.0e+00
(pic) (net)

-16.41
2.4e-01
(pic) (net)

-16.46
7.3e-01
(pic) (net) Clust=( 0.45 0.55 )

-16.82
1.0e-00
(pic) (net) Clust=( 0.41 0.59 )

11

P$ABF1_01

20 samples

-39.87
1.0e+00
(pic) (net)

-33.22
4.5e-07
(pic) (net)

-36.18
5.5e-05
(pic) (net) Clust=( 0.38 0.62 )

-33.33
8.2e-06
(pic) (net) Clust=( 0.62 0.38 )

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

12

P$ABF_Q2

49 samples

-20.50
1.0e+00
(pic) (net)

-19.13
4.7e-05
(pic) (net)

-19.65
1.4e-05
(pic) (net) Clust=( 0.75 0.25 )

-18.79
1.4e-04
(pic) (net) Clust=( 0.29 0.71 )

13

P$ANT_01

34 samples

-14.11
1.0e+00
(pic) (net)

-12.76
5.4e-03
(pic) (net)

-12.02
1.5e-02
(pic) (net) Clust=( 0.88 0.12 )

-12.29
2.8e-02
(pic) (net) Clust=( 0.88 0.12 )

14

P$ATHB1_01

25 samples

-11.71
1.0e+00
(pic) (net)

-11.71
6.8e-01
(pic) (net)

-11.56
9.6e-02
(pic) (net) Clust=( 0.92 0.08 )

-11.35
1.1e-02
(pic) (net) Clust=( 0.92 0.08 )

15

P$ATHB5_01

39 samples

-5.90
1.0e+00
(pic) (net)

-5.31
3.4e-07
(pic) (net)

-5.19
6.6e-03
(pic) (net) Clust=( 0.81 0.19 )

-5.08
2.2e-03
(pic) (net) Clust=( 0.10 0.90 )

16

P$EMBP1_Q2

24 samples

-9.56
1.0e+00
(pic) (net)

-8.55
4.0e-06
(pic) (net)

-9.23
2.6e-03
(pic) (net) Clust=( 0.12 0.88 )

-8.43
1.2e-05
(pic) (net) Clust=( 0.88 0.12 )

17

P$GAMYB_01

25 samples

-8.16
1.0e+00
(pic) (net)

-8.16
1.0e+00
(pic) (net)

-7.92
7.3e-03
(pic) (net) Clust=( 0.51 0.49 )

-8.03
1.6e-01
(pic) (net) Clust=( 0.79 0.21 )

18

P$LIM1_01

20 samples

-20.25
1.0e+00
(pic) (net)

-20.32
7.5e-01
(pic) (net)

-20.30
5.6e-01
(pic) (net) Clust=( 0.42 0.58 )

-20.25
5.0e-01
(pic) (net) Clust=( 0.29 0.71 )

19

P$P_01

36 samples

-9.37
1.0e+00
(pic) (net)

-9.37
1.0e+00
(pic) (net)

-9.34
4.3e-01
(pic) (net) Clust=( 0.27 0.73 )

-9.25
1.7e-01
(pic) (net) Clust=( 0.73 0.27 )

20

V$AHRARNT_01

24 samples

-23.80
1.0e+00
(pic) (net)

-21.42
4.5e-03
(pic) (net)

-21.77
6.2e-05
(pic) (net) Clust=( 0.60 0.40 )

-21.48
2.5e-05
(pic) (net) Clust=( 0.60 0.40 )

21

V$AHRARNT_02

25 samples

-21.47
1.0e+00
(pic) (net)

-21.65
8.0e-01
(pic) (net)

-21.61
6.8e-01
(pic) (net) Clust=( 0.50 0.50 )

-20.89
1.1e-01
(pic) (net) Clust=( 0.51 0.49 )

22

V$AML1_01

56 samples

-3.36
1.0e+00
(pic) (net)

-3.36
1.0e+00
(pic) (net)

-3.32
1.1e-01
(pic) (net) Clust=( 0.96 0.04 )

-3.30
5.9e-02
(pic) (net) Clust=( 0.96 0.04 )

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

23

V$ARNT_01

20 samples

-22.99
1.0e+00
(pic) (net)

-24.95
1.0e-00
(pic) (net)

-22.31
1.6e-01
(pic) (net) Clust=( 0.46 0.54 )

-22.61
3.1e-01
(pic) (net) Clust=( 0.54 0.46 )

24

V$AR_01

29 samples

-17.85
1.0e+00
(pic) (net)

-17.85
1.0e+00
(pic) (net)

-17.58
2.2e-02
(pic) (net) Clust=( 0.84 0.16 )

-17.59
1.5e-01
(pic) (net) Clust=( 0.44 0.56 )

25

V$ATF6_01

20 samples

-2.94
1.0e+00
(pic) (net)

-2.39
1.1e-03
(pic) (net)

-2.25
1.0e-10
(pic) (net) Clust=( 0.10 0.90 )

-1.71
2.9e-08
(pic) (net) Clust=( 0.10 0.90 )

26

V$ATF_01

25 samples

-17.92
1.0e+00
(pic) (net)

-17.76
2.1e-01
(pic) (net)

-17.76
2.5e-01
(pic) (net) Clust=( 0.92 0.08 )

-16.80
2.7e-03
(pic) (net) Clust=( 0.35 0.65 )

27

V$BRACH_01

40 samples

-21.18
1.0e+00
(pic) (net)

-19.55
1.5e-02
(pic) (net)

-20.65
7.1e-02
(pic) (net) Clust=( 0.79 0.21 )

-17.96
4.9e-03
(pic) (net) Clust=( 0.06 0.94 )

28

V$CART1_01

25 samples

-24.21
1.0e+00
(pic) (net)

-24.56
9.7e-01
(pic) (net)

-24.20
4.8e-01
(pic) (net) Clust=( 0.42 0.58 )

-24.85
9.8e-01
(pic) (net) Clust=( 0.15 0.85 )

29

V$CDPCR1_01

32 samples

-11.19
1.0e+00
(pic) (net)

-11.28
8.7e-01
(pic) (net)

-11.44
9.7e-01
(pic) (net) Clust=( 0.37 0.63 )

-11.36
8.4e-01
(pic) (net) Clust=( 0.29 0.71 )

30

V$CDPCR3HD_01

33 samples

-10.75
1.0e+00
(pic) (net)

-10.75
1.0e+00
(pic) (net)

-10.57
1.4e-01
(pic) (net) Clust=( 0.57 0.43 )

-10.78
6.0e-01
(pic) (net) Clust=( 0.52 0.48 )

31

V$CDPCR3_01

24 samples

-16.14
1.0e+00
(pic) (net)

-15.75
7.4e-03
(pic) (net)

-15.88
8.4e-02
(pic) (net) Clust=( 0.19 0.81 )

-15.77
5.5e-02
(pic) (net) Clust=( 0.88 0.12 )

32

V$CEBPA_01

43 samples

-20.16
1.0e+00
(pic) (net)

-20.16
1.0e+00
(pic) (net)

-20.47
9.6e-01
(pic) (net) Clust=( 0.46 0.54 )

-20.23
6.4e-01
(pic) (net) Clust=( 0.50 0.50 )

33

V$CEBPB_01

21 samples

-19.99
1.0e+00
(pic) (net)

-19.99
1.0e+00
(pic) (net)

-20.30
8.6e-01
(pic) (net) Clust=( 0.60 0.40 )

-20.24
7.6e-01
(pic) (net) Clust=( 0.10 0.90 )

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

34

V$CEBP_01

22 samples

-21.34
1.0e+00
(pic) (net)

-21.56
9.2e-01
(pic) (net)

-21.82
9.9e-01
(pic) (net) Clust=( 0.79 0.21 )

-21.88
9.3e-01
(pic) (net) Clust=( 0.49 0.51 )

35

V$CETS1P54_02

40 samples

-18.66
1.0e+00
(pic) (net)

-18.86
9.4e-01
(pic) (net)

-18.96
9.6e-01
(pic) (net) Clust=( 0.59 0.41 )

-18.98
9.8e-01
(pic) (net) Clust=( 0.32 0.68 )

36

V$CHX10_01

20 samples

-20.17
1.0e+00
(pic) (net)

-18.15
2.1e-02
(pic) (net)

-18.13
1.3e-03
(pic) (net) Clust=( 0.78 0.22 )

-17.89
3.0e-03
(pic) (net) Clust=( 0.26 0.74 )

37

V$CIZ_01

39 samples

-7.69
1.0e+00
(pic) (net)

-7.67
4.3e-01
(pic) (net)

-7.57
9.8e-02
(pic) (net) Clust=( 0.57 0.43 )

-7.26
2.1e-03
(pic) (net) Clust=( 0.06 0.94 )

38

V$E4BP4_01

23 samples

-11.19
1.0e+00
(pic) (net)

-11.19
1.0e+00
(pic) (net)

-10.70
9.8e-07
(pic) (net) Clust=( 0.09 0.91 )

-11.05
3.5e-01
(pic) (net) Clust=( 0.91 0.09 )

39

V$ELK1_02

31 samples

-19.85
1.0e+00
(pic) (net)

-19.85
1.0e+00
(pic) (net)

-19.95
6.8e-01
(pic) (net) Clust=( 0.17 0.83 )

-19.71
3.1e-01
(pic) (net) Clust=( 0.41 0.59 )

40

V$ERR1_Q2

25 samples

-18.87
1.0e+00
(pic) (net)

-18.96
8.1e-01
(pic) (net)

-18.90
5.6e-01
(pic) (net) Clust=( 0.46 0.54 )

-19.77
9.9e-01
(pic) (net) Clust=( 0.48 0.52 )

41

V$EVI1_03

27 samples

-4.95
1.0e+00
(pic) (net)

-4.97
5.7e-01
(pic) (net)

-4.25
1.1e-08
(pic) (net) Clust=( 0.08 0.92 )

-4.31
2.4e-04
(pic) (net) Clust=( 0.92 0.08 )

42

V$FAC1_01

24 samples

-22.55
1.0e+00
(pic) (net)

-22.36
2.9e-01
(pic) (net)

-22.56
5.1e-01
(pic) (net) Clust=( 0.63 0.37 )

-22.98
7.3e-01
(pic) (net) Clust=( 0.12 0.88 )

43

V$FOXD3_01

32 samples

-13.95
1.0e+00
(pic) (net)

-14.38
9.2e-01
(pic) (net)

-13.48
8.6e-02
(pic) (net) Clust=( 0.46 0.54 )

-13.08
5.8e-02
(pic) (net) Clust=( 0.07 0.93 )

44

V$FOXJ2_01

41 samples

-24.18
1.0e+00
(pic) (net)

-23.59
1.8e-04
(pic) (net)

-24.63
1.0e-00
(pic) (net) Clust=( 0.05 0.95 )

-23.75
3.3e-02
(pic) (net) Clust=( 0.05 0.95 )

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

45

V$FOXO1_02

21 samples

-16.15
1.0e+00
(pic) (net)

-16.47
7.8e-01
(pic) (net)

-15.80
4.2e-02
(pic) (net) Clust=( 0.87 0.13 )

-16.56
7.5e-01
(pic) (net) Clust=( 0.83 0.17 )

46

V$FOXO4_01

30 samples

-12.99
1.0e+00
(pic) (net)

-12.99
1.0e+00
(pic) (net)

-12.96
4.4e-01
(pic) (net) Clust=( 0.70 0.30 )

-12.76
5.7e-02
(pic) (net) Clust=( 0.77 0.23 )

47

V$GATA6_01

69 samples

-13.76
1.0e+00
(pic) (net)

-13.76
1.0e+00
(pic) (net)

-13.92
9.2e-01
(pic) (net) Clust=( 0.83 0.17 )

-13.87
8.0e-01
(pic) (net) Clust=( 0.29 0.71 )

48

V$GKLF_01

49 samples

-20.56
1.0e+00
(pic) (net)

-20.32
9.6e-03
(pic) (net)

-20.70
8.3e-01
(pic) (net) Clust=( 0.63 0.37 )

-20.42
1.7e-01
(pic) (net) Clust=( 0.12 0.88 )

49

V$GNCF_01

37 samples

-10.51
1.0e+00
(pic) (net)

-10.63
9.2e-01
(pic) (net)

-10.25
1.3e-02
(pic) (net) Clust=( 0.06 0.94 )

-10.42
3.1e-01
(pic) (net) Clust=( 0.94 0.06 )

50

V$HAND1E47_01

29 samples

-23.22
1.0e+00
(pic) (net)

-23.11
3.0e-01
(pic) (net)

-23.31
6.2e-01
(pic) (net) Clust=( 0.59 0.41 )

-23.56
8.1e-01
(pic) (net) Clust=( 0.38 0.62 )

51

V$HNF1_01

26 samples

-17.89
1.0e+00
(pic) (net)

-17.98
8.2e-01
(pic) (net)

-17.97
6.6e-01
(pic) (net) Clust=( 0.75 0.25 )

-18.30
9.0e-01
(pic) (net) Clust=( 0.08 0.92 )

52

V$IRF1_01

21 samples

-15.55
1.0e+00
(pic) (net)

-15.35
4.1e-01
(pic) (net)

-14.68
3.2e-02
(pic) (net) Clust=( 0.67 0.33 )

-13.74
3.4e-02
(pic) (net) Clust=( 0.13 0.87 )

53

V$IRF7_01

28 samples

-30.82
1.0e+00
(pic) (net)

-29.52
1.0e-01
(pic) (net)

-27.56
1.7e-04
(pic) (net) Clust=( 0.29 0.71 )

-28.46
1.4e-02
(pic) (net) Clust=( 0.29 0.71 )

54

V$LHX3_01

40 samples

-7.36
1.0e+00
(pic) (net)

-7.43
7.8e-01
(pic) (net)

-7.14
2.7e-03
(pic) (net) Clust=( 0.90 0.10 )

-7.13
4.3e-02
(pic) (net) Clust=( 0.94 0.06 )

55

V$LUN1_01

24 samples

-10.46
1.0e+00
(pic) (net)

-7.87
1.6e-07
(pic) (net)

-9.52
3.4e-04
(pic) (net) Clust=( 0.19 0.81 )

-6.92
4.1e-09
(pic) (net) Clust=( 0.09 0.91 )

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

56

V$MZF1_01

20 samples

-8.59
1.0e+00
(pic) (net)

-8.36
0.0e+00
(pic) (net)

-8.42
1.3e-01
(pic) (net) Clust=( 0.18 0.82 )

-8.61
5.3e-01
(pic) (net) Clust=( 0.90 0.10 )

57

V$NCX_01

40 samples

-16.22
1.0e+00
(pic) (net)

-16.22
1.0e+00
(pic) (net)

-16.28
6.5e-01
(pic) (net) Clust=( 0.28 0.72 )

-16.21
4.9e-01
(pic) (net) Clust=( 0.41 0.59 )

58

V$NFKAPPAB_01

40 samples

-7.78
1.0e+00
(pic) (net)

-7.73
2.2e-01
(pic) (net)

-7.67
9.5e-02
(pic) (net) Clust=( 0.06 0.94 )

-7.70
3.1e-01
(pic) (net) Clust=( 0.73 0.27 )

59

V$NKX22_01

23 samples

-10.70
1.0e+00
(pic) (net)

-9.38
5.0e-03
(pic) (net)

-9.08
1.8e-04
(pic) (net) Clust=( 0.23 0.77 )

-9.09
9.2e-04
(pic) (net) Clust=( 0.09 0.91 )

60

V$NRSF_01

28 samples

-15.76
1.0e+00
(pic) (net)

-15.60
3.8e-01
(pic) (net)

-15.07
3.5e-04
(pic) (net) Clust=( 0.76 0.24 )

-15.15
1.8e-01
(pic) (net) Clust=( 0.92 0.08 )

61

V$OCT1_01

56 samples

-18.97
1.0e+00
(pic) (net)

-18.92
1.5e-02
(pic) (net)

-18.94
3.8e-01
(pic) (net) Clust=( 0.66 0.34 )

-18.91
3.4e-01
(pic) (net) Clust=( 0.96 0.04 )

62

V$OCT1_02

44 samples

-18.08
1.0e+00
(pic) (net)

-18.08
1.0e+00
(pic) (net)

-18.39
9.8e-01
(pic) (net) Clust=( 0.65 0.35 )

-18.54
1.0e-00
(pic) (net) Clust=( 0.93 0.07 )

63

V$OCT1_03

51 samples

-17.18
1.0e+00
(pic) (net)

-17.18
4.2e-02
(pic) (net)

-17.25
6.6e-01
(pic) (net) Clust=( 0.50 0.50 )

-17.30
7.7e-01
(pic) (net) Clust=( 0.41 0.59 )

64

V$OCT1_04

47 samples

-30.85
1.0e+00
(pic) (net)

-30.94
8.9e-01
(pic) (net)

-31.33
9.9e-01
(pic) (net) Clust=( 0.44 0.56 )

-31.79
1.0e+00
(pic) (net) Clust=( 0.60 0.40 )

65

V$PAX2_01

32 samples

-29.92
1.0e+00
(pic) (net)

-30.03
8.8e-01
(pic) (net)

-30.07
6.4e-01
(pic) (net) Clust=( 0.53 0.47 )

-29.50
2.2e-01
(pic) (net) Clust=( 0.69 0.31 )

66

V$PAX2_02

37 samples

-12.64
1.0e+00
(pic) (net)

-12.64
1.0e+00
(pic) (net)

-12.78
8.0e-01
(pic) (net) Clust=( 0.49 0.51 )

-12.93
9.3e-01
(pic) (net) Clust=( 0.06 0.94 )

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

67

V$PAX6_01

47 samples

-27.02
1.0e+00
(pic) (net)

-26.90
2.0e-01
(pic) (net)

-26.85
2.8e-01
(pic) (net) Clust=( 0.89 0.11 )

-27.19
6.6e-01
(pic) (net) Clust=( 0.56 0.44 )

68

V$PAX8_01

35 samples

-26.93
1.0e+00
(pic) (net)

-26.93
1.0e+00
(pic) (net)

-27.18
7.8e-01
(pic) (net) Clust=( 0.46 0.54 )

-26.97
5.4e-01
(pic) (net) Clust=( 0.25 0.75 )

69

V$PAX8_B

23 samples

-32.75
1.0e+00
(pic) (net)

-33.10
9.6e-01
(pic) (net)

-34.15
1.0e+00
(pic) (net) Clust=( 0.55 0.45 )

-34.45
1.0e-00
(pic) (net) Clust=( 0.45 0.55 )

70

V$PBX1_02

40 samples

-20.04
1.0e+00
(pic) (net)

-17.73
3.3e-03
(pic) (net)

-17.85
7.4e-05
(pic) (net) Clust=( 0.21 0.79 )

-17.18
4.0e-04
(pic) (net) Clust=( 0.21 0.79 )

71

V$PPARG_01

72 samples

-24.32
1.0e+00
(pic) (net)

-18.08
1.2e-07
(pic) (net)

-18.54
1.8e-08
(pic) (net) Clust=( 0.81 0.19 )

-17.45
1.2e-07
(pic) (net) Clust=( 0.81 0.19 )

72

V$PPARG_02

28 samples

-29.79
1.0e+00
(pic) (net)

-27.08
7.8e-03
(pic) (net)

-24.32
1.8e-05
(pic) (net) Clust=( 0.23 0.77 )

-24.53
2.2e-04
(pic) (net) Clust=( 0.77 0.23 )

73

V$RORA1_01

25 samples

-14.73
1.0e+00
(pic) (net)

-14.73
1.0e+00
(pic) (net)

-14.67
3.3e-01
(pic) (net) Clust=( 0.29 0.71 )

-14.35
4.1e-05
(pic) (net) Clust=( 0.92 0.08 )

74

V$RORA2_01

36 samples

-10.45
1.0e+00
(pic) (net)

-10.45
1.0e+00
(pic) (net)

-9.97
0.0e+00
(pic) (net) Clust=( 0.06 0.94 )

-9.94
0.0e+00
(pic) (net) Clust=( 0.26 0.74 )

75

V$RSRFC4_01

38 samples

-15.60
1.0e+00
(pic) (net)

-15.60
1.0e+00
(pic) (net)

-15.23
6.9e-06
(pic) (net) Clust=( 0.06 0.94 )

-15.23
6.5e-06
(pic) (net) Clust=( 0.25 0.75 )

76

V$RSRFC4_Q2

27 samples

-23.13
1.0e+00
(pic) (net)

-19.70
1.2e-05
(pic) (net)

-20.28
9.0e-06
(pic) (net) Clust=( 0.73 0.27 )

-19.60
4.9e-06
(pic) (net) Clust=( 0.71 0.29 )

77

V$R_01

35 samples

-26.84
1.0e+00
(pic) (net)

-27.03
8.9e-01
(pic) (net)

-27.03
8.5e-01
(pic) (net) Clust=( 0.09 0.91 )

-27.31
9.0e-01
(pic) (net) Clust=( 0.18 0.82 )

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

78

V$S8_01

59 samples

-20.85
1.0e+00
(pic) (net)

-19.28
6.7e-05
(pic) (net)

-19.57
3.3e-06
(pic) (net) Clust=( 0.54 0.46 )

-19.63
1.4e-02
(pic) (net) Clust=( 0.37 0.63 )

79

V$SOX5_01

23 samples

-10.63
1.0e+00
(pic) (net)

-10.63
1.0e+00
(pic) (net)

-10.47
6.1e-02
(pic) (net) Clust=( 0.09 0.91 )

-10.48
7.7e-02
(pic) (net) Clust=( 0.15 0.85 )

80

V$SOX9_B1

73 samples

-17.84
1.0e+00
(pic) (net)

-17.66
4.2e-02
(pic) (net)

-17.47
1.9e-02
(pic) (net) Clust=( 0.29 0.71 )

-17.27
2.2e-03
(pic) (net) Clust=( 0.21 0.79 )

81

V$SPZ1_01

30 samples

-24.90
1.0e+00
(pic) (net)

-24.92
6.5e-01
(pic) (net)

-24.65
2.6e-01
(pic) (net) Clust=( 0.58 0.42 )

-25.20
8.1e-01
(pic) (net) Clust=( 0.56 0.44 )

82

V$SRY_01

23 samples

-8.59
1.0e+00
(pic) (net)

-8.59
1.0e+00
(pic) (net)

-8.65
7.6e-01
(pic) (net) Clust=( 0.87 0.13 )

-8.71
9.2e-01
(pic) (net) Clust=( 0.87 0.13 )

83

V$SRY_02

29 samples

-15.84
1.0e+00
(pic) (net)

-15.84
1.0e+00
(pic) (net)

-16.34
1.0e-00
(pic) (net) Clust=( 0.77 0.23 )

-16.16
9.8e-01
(pic) (net) Clust=( 0.71 0.29 )

84

V$STAT5A_01

33 samples

-20.69
1.0e+00
(pic) (net)

-19.39
1.7e-02
(pic) (net)

-18.71
4.3e-03
(pic) (net) Clust=( 0.80 0.20 )

-18.28
5.2e-03
(pic) (net) Clust=( 0.78 0.22 )

85

V$STAT5A_02

37 samples

-35.50
1.0e+00
(pic) (net)

-35.50
1.0e+00
(pic) (net)

-35.54
5.8e-01
(pic) (net) Clust=( 0.51 0.49 )

-36.12
1.0e-00
(pic) (net) Clust=( 0.56 0.44 )

86

V$STAT5B_01

46 samples

-18.36
1.0e+00
(pic) (net)

-17.13
1.1e-03
(pic) (net)

-16.33
1.5e-03
(pic) (net) Clust=( 0.13 0.87 )

-16.57
4.3e-03
(pic) (net) Clust=( 0.34 0.66 )

87

V$TBP_01

47 samples

-7.13
1.0e+00
(pic) (net)

-6.81
3.1e-02
(pic) (net)

-6.98
1.3e-02
(pic) (net) Clust=( 0.05 0.95 )

-6.49
2.4e-04
(pic) (net) Clust=( 0.95 0.05 )

88

V$VJUN_01

24 samples

-14.77
1.0e+00
(pic) (net)

-14.77
1.0e+00
(pic) (net)

-14.05
1.7e-09
(pic) (net) Clust=( 0.09 0.91 )

-13.92
8.3e-09
(pic) (net) Clust=( 0.09 0.91 )

#

NAME

DATA

PSSM
(likelihood,pval)

Tree
(likelihood,pval)

Mixture of PSSMs
(likelihood,pval)

Mixture of Trees
(likelihood,pval)

89

V$VMYB_01

24 samples

-12.48
1.0e+00
(pic) (net)

-13.01
8.7e-01
(pic) (net)

-12.32
3.3e-01
(pic) (net) Clust=( 0.67 0.33 )

-12.29
3.6e-01
(pic) (net) Clust=( 0.67 0.33 )

90

V$VMYB_02

29 samples

-8.62
1.0e+00
(pic) (net)

-8.62
1.0e+00
(pic) (net)

-8.33
4.3e-04
(pic) (net) Clust=( 0.07 0.93 )

-8.66
5.5e-01
(pic) (net) Clust=( 0.93 0.07 )

91

V$XBP1_01

33 samples

-22.71
1.0e+00
(pic) (net)

-22.87
9.0e-01
(pic) (net)

-22.84
7.1e-01
(pic) (net) Clust=( 0.59 0.41 )

-22.87
7.0e-01
(pic) (net) Clust=( 0.60 0.40 )

92

V$ZIC1_01

30 samples

-13.60
1.0e+00
(pic) (net)

-13.60
1.0e+00
(pic) (net)

-13.85
9.5e-01
(pic) (net) Clust=( 0.59 0.41 )

-13.89
9.8e-01
(pic) (net) Clust=( 0.41 0.59 )

93

V$ZIC2_01

30 samples

-13.66
1.0e+00
(pic) (net)

-13.66
1.0e+00
(pic) (net)

-14.06
1.0e-00
(pic) (net) Clust=( 0.57 0.43 )

-14.06
1.0e-00
(pic) (net) Clust=( 0.51 0.49 )

94

V$ZIC3_01

35 samples

-13.25
1.0e+00
(pic) (net)

-13.25
1.0e+00
(pic) (net)

-13.56
9.9e-01
(pic) (net) Clust=( 0.60 0.40 )

-13.44
9.4e-01
(pic) (net) Clust=( 0.84 0.16 )

95

V$ZID_01

35 samples

-13.31
1.0e+00
(pic) (net)

-13.57
9.5e-01
(pic) (net)

-13.09
4.2e-02
(pic) (net) Clust=( 0.50 0.50 )

-13.35
5.7e-01
(pic) (net) Clust=( 0.94 0.06 )

#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
1	F$ABAA_01	22 samples	-27.67 1.0e+00 (pic) (net)	-27.78 8.2e-01 (pic) (net)	-27.83 7.1e-01 (pic) (net) Clust=( 0.32 0.68 )	-28.92 1.0e-00 (pic) (net) Clust=( 0.65 0.35 )
2	F$GCN4_01	43 samples	-27.32 1.0e+00 (pic) (net)	-27.33 9.6e-01 (pic) (net)	-27.82 1.0e-00 (pic) (net) Clust=( 0.26 0.74 )	-27.79 9.9e-01 (pic) (net) Clust=( 0.30 0.70 )
3	F$MCM1_01	23 samples	-21.11 1.0e+00 (pic) (net)	-21.11 1.0e+00 (pic) (net)	-21.23 7.5e-01 (pic) (net) Clust=( 0.70 0.30 )	-21.77 9.5e-01 (pic) (net) Clust=( 0.34 0.66 )
4	I$CF1_02	38 samples	-5.57 1.0e+00 (pic) (net)	-5.56 4.7e-01 (pic) (net)	-5.29 3.3e-03 (pic) (net) Clust=( 0.94 0.06 )	-5.13 3.5e-05 (pic) (net) Clust=( 0.06 0.94 )
5	I$CF2II_01	80 samples	-7.78 1.0e+00 (pic) (net)	-7.78 1.0e+00 (pic) (net)	-7.60 5.9e-02 (pic) (net) Clust=( 0.94 0.06 )	-7.53 3.1e-02 (pic) (net) Clust=( 0.94 0.06 )
6	I$DL_01	22 samples	-9.07 1.0e+00 (pic) (net)	-9.07 1.0e+00 (pic) (net)	-8.74 4.2e-03 (pic) (net) Clust=( 0.09 0.91 )	-8.82 4.4e-02 (pic) (net) Clust=( 0.09 0.91 )
7	I$DRI_01	42 samples	-11.85 1.0e+00 (pic) (net)	-11.85 1.0e+00 (pic) (net)	-11.81 4.0e-01 (pic) (net) Clust=( 0.72 0.28 )	-11.72 2.6e-01 (pic) (net) Clust=( 0.70 0.30 )
8	I$OVO_01	21 samples	-22.81 1.0e+00 (pic) (net)	-22.81 1.0e+00 (pic) (net)	-23.36 9.8e-01 (pic) (net) Clust=( 0.56 0.44 )	-23.35 9.9e-01 (pic) (net) Clust=( 0.55 0.45 )
9	I$SN_01	40 samples	-11.56 1.0e+00 (pic) (net)	-11.47 1.7e-02 (pic) (net)	-11.45 1.2e-01 (pic) (net) Clust=( 0.08 0.92 )	-11.51 3.7e-01 (pic) (net) Clust=( 0.08 0.92 )
10	I$UBX_01	88 samples	-16.41 1.0e+00 (pic) (net)	-16.41 2.4e-01 (pic) (net)	-16.46 7.3e-01 (pic) (net) Clust=( 0.45 0.55 )	-16.82 1.0e-00 (pic) (net) Clust=( 0.41 0.59 )
11	P$ABF1_01	20 samples	-39.87 1.0e+00 (pic) (net)	-33.22 4.5e-07 (pic) (net)	-36.18 5.5e-05 (pic) (net) Clust=( 0.38 0.62 )	-33.33 8.2e-06 (pic) (net) Clust=( 0.62 0.38 )
#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
12	P$ABF_Q2	49 samples	-20.50 1.0e+00 (pic) (net)	-19.13 4.7e-05 (pic) (net)	-19.65 1.4e-05 (pic) (net) Clust=( 0.75 0.25 )	-18.79 1.4e-04 (pic) (net) Clust=( 0.29 0.71 )
13	P$ANT_01	34 samples	-14.11 1.0e+00 (pic) (net)	-12.76 5.4e-03 (pic) (net)	-12.02 1.5e-02 (pic) (net) Clust=( 0.88 0.12 )	-12.29 2.8e-02 (pic) (net) Clust=( 0.88 0.12 )
14	P$ATHB1_01	25 samples	-11.71 1.0e+00 (pic) (net)	-11.71 6.8e-01 (pic) (net)	-11.56 9.6e-02 (pic) (net) Clust=( 0.92 0.08 )	-11.35 1.1e-02 (pic) (net) Clust=( 0.92 0.08 )
15	P$ATHB5_01	39 samples	-5.90 1.0e+00 (pic) (net)	-5.31 3.4e-07 (pic) (net)	-5.19 6.6e-03 (pic) (net) Clust=( 0.81 0.19 )	-5.08 2.2e-03 (pic) (net) Clust=( 0.10 0.90 )
16	P$EMBP1_Q2	24 samples	-9.56 1.0e+00 (pic) (net)	-8.55 4.0e-06 (pic) (net)	-9.23 2.6e-03 (pic) (net) Clust=( 0.12 0.88 )	-8.43 1.2e-05 (pic) (net) Clust=( 0.88 0.12 )
17	P$GAMYB_01	25 samples	-8.16 1.0e+00 (pic) (net)	-8.16 1.0e+00 (pic) (net)	-7.92 7.3e-03 (pic) (net) Clust=( 0.51 0.49 )	-8.03 1.6e-01 (pic) (net) Clust=( 0.79 0.21 )
18	P$LIM1_01	20 samples	-20.25 1.0e+00 (pic) (net)	-20.32 7.5e-01 (pic) (net)	-20.30 5.6e-01 (pic) (net) Clust=( 0.42 0.58 )	-20.25 5.0e-01 (pic) (net) Clust=( 0.29 0.71 )
19	P$P_01	36 samples	-9.37 1.0e+00 (pic) (net)	-9.37 1.0e+00 (pic) (net)	-9.34 4.3e-01 (pic) (net) Clust=( 0.27 0.73 )	-9.25 1.7e-01 (pic) (net) Clust=( 0.73 0.27 )
20	V$AHRARNT_01	24 samples	-23.80 1.0e+00 (pic) (net)	-21.42 4.5e-03 (pic) (net)	-21.77 6.2e-05 (pic) (net) Clust=( 0.60 0.40 )	-21.48 2.5e-05 (pic) (net) Clust=( 0.60 0.40 )
21	V$AHRARNT_02	25 samples	-21.47 1.0e+00 (pic) (net)	-21.65 8.0e-01 (pic) (net)	-21.61 6.8e-01 (pic) (net) Clust=( 0.50 0.50 )	-20.89 1.1e-01 (pic) (net) Clust=( 0.51 0.49 )
22	V$AML1_01	56 samples	-3.36 1.0e+00 (pic) (net)	-3.36 1.0e+00 (pic) (net)	-3.32 1.1e-01 (pic) (net) Clust=( 0.96 0.04 )	-3.30 5.9e-02 (pic) (net) Clust=( 0.96 0.04 )
#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
23	V$ARNT_01	20 samples	-22.99 1.0e+00 (pic) (net)	-24.95 1.0e-00 (pic) (net)	-22.31 1.6e-01 (pic) (net) Clust=( 0.46 0.54 )	-22.61 3.1e-01 (pic) (net) Clust=( 0.54 0.46 )
24	V$AR_01	29 samples	-17.85 1.0e+00 (pic) (net)	-17.85 1.0e+00 (pic) (net)	-17.58 2.2e-02 (pic) (net) Clust=( 0.84 0.16 )	-17.59 1.5e-01 (pic) (net) Clust=( 0.44 0.56 )
25	V$ATF6_01	20 samples	-2.94 1.0e+00 (pic) (net)	-2.39 1.1e-03 (pic) (net)	-2.25 1.0e-10 (pic) (net) Clust=( 0.10 0.90 )	-1.71 2.9e-08 (pic) (net) Clust=( 0.10 0.90 )
26	V$ATF_01	25 samples	-17.92 1.0e+00 (pic) (net)	-17.76 2.1e-01 (pic) (net)	-17.76 2.5e-01 (pic) (net) Clust=( 0.92 0.08 )	-16.80 2.7e-03 (pic) (net) Clust=( 0.35 0.65 )
27	V$BRACH_01	40 samples	-21.18 1.0e+00 (pic) (net)	-19.55 1.5e-02 (pic) (net)	-20.65 7.1e-02 (pic) (net) Clust=( 0.79 0.21 )	-17.96 4.9e-03 (pic) (net) Clust=( 0.06 0.94 )
28	V$CART1_01	25 samples	-24.21 1.0e+00 (pic) (net)	-24.56 9.7e-01 (pic) (net)	-24.20 4.8e-01 (pic) (net) Clust=( 0.42 0.58 )	-24.85 9.8e-01 (pic) (net) Clust=( 0.15 0.85 )
29	V$CDPCR1_01	32 samples	-11.19 1.0e+00 (pic) (net)	-11.28 8.7e-01 (pic) (net)	-11.44 9.7e-01 (pic) (net) Clust=( 0.37 0.63 )	-11.36 8.4e-01 (pic) (net) Clust=( 0.29 0.71 )
30	V$CDPCR3HD_01	33 samples	-10.75 1.0e+00 (pic) (net)	-10.75 1.0e+00 (pic) (net)	-10.57 1.4e-01 (pic) (net) Clust=( 0.57 0.43 )	-10.78 6.0e-01 (pic) (net) Clust=( 0.52 0.48 )
31	V$CDPCR3_01	24 samples	-16.14 1.0e+00 (pic) (net)	-15.75 7.4e-03 (pic) (net)	-15.88 8.4e-02 (pic) (net) Clust=( 0.19 0.81 )	-15.77 5.5e-02 (pic) (net) Clust=( 0.88 0.12 )
32	V$CEBPA_01	43 samples	-20.16 1.0e+00 (pic) (net)	-20.16 1.0e+00 (pic) (net)	-20.47 9.6e-01 (pic) (net) Clust=( 0.46 0.54 )	-20.23 6.4e-01 (pic) (net) Clust=( 0.50 0.50 )
33	V$CEBPB_01	21 samples	-19.99 1.0e+00 (pic) (net)	-19.99 1.0e+00 (pic) (net)	-20.30 8.6e-01 (pic) (net) Clust=( 0.60 0.40 )	-20.24 7.6e-01 (pic) (net) Clust=( 0.10 0.90 )
#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
34	V$CEBP_01	22 samples	-21.34 1.0e+00 (pic) (net)	-21.56 9.2e-01 (pic) (net)	-21.82 9.9e-01 (pic) (net) Clust=( 0.79 0.21 )	-21.88 9.3e-01 (pic) (net) Clust=( 0.49 0.51 )
35	V$CETS1P54_02	40 samples	-18.66 1.0e+00 (pic) (net)	-18.86 9.4e-01 (pic) (net)	-18.96 9.6e-01 (pic) (net) Clust=( 0.59 0.41 )	-18.98 9.8e-01 (pic) (net) Clust=( 0.32 0.68 )
36	V$CHX10_01	20 samples	-20.17 1.0e+00 (pic) (net)	-18.15 2.1e-02 (pic) (net)	-18.13 1.3e-03 (pic) (net) Clust=( 0.78 0.22 )	-17.89 3.0e-03 (pic) (net) Clust=( 0.26 0.74 )
37	V$CIZ_01	39 samples	-7.69 1.0e+00 (pic) (net)	-7.67 4.3e-01 (pic) (net)	-7.57 9.8e-02 (pic) (net) Clust=( 0.57 0.43 )	-7.26 2.1e-03 (pic) (net) Clust=( 0.06 0.94 )
38	V$E4BP4_01	23 samples	-11.19 1.0e+00 (pic) (net)	-11.19 1.0e+00 (pic) (net)	-10.70 9.8e-07 (pic) (net) Clust=( 0.09 0.91 )	-11.05 3.5e-01 (pic) (net) Clust=( 0.91 0.09 )
39	V$ELK1_02	31 samples	-19.85 1.0e+00 (pic) (net)	-19.85 1.0e+00 (pic) (net)	-19.95 6.8e-01 (pic) (net) Clust=( 0.17 0.83 )	-19.71 3.1e-01 (pic) (net) Clust=( 0.41 0.59 )
40	V$ERR1_Q2	25 samples	-18.87 1.0e+00 (pic) (net)	-18.96 8.1e-01 (pic) (net)	-18.90 5.6e-01 (pic) (net) Clust=( 0.46 0.54 )	-19.77 9.9e-01 (pic) (net) Clust=( 0.48 0.52 )
41	V$EVI1_03	27 samples	-4.95 1.0e+00 (pic) (net)	-4.97 5.7e-01 (pic) (net)	-4.25 1.1e-08 (pic) (net) Clust=( 0.08 0.92 )	-4.31 2.4e-04 (pic) (net) Clust=( 0.92 0.08 )
42	V$FAC1_01	24 samples	-22.55 1.0e+00 (pic) (net)	-22.36 2.9e-01 (pic) (net)	-22.56 5.1e-01 (pic) (net) Clust=( 0.63 0.37 )	-22.98 7.3e-01 (pic) (net) Clust=( 0.12 0.88 )
43	V$FOXD3_01	32 samples	-13.95 1.0e+00 (pic) (net)	-14.38 9.2e-01 (pic) (net)	-13.48 8.6e-02 (pic) (net) Clust=( 0.46 0.54 )	-13.08 5.8e-02 (pic) (net) Clust=( 0.07 0.93 )
44	V$FOXJ2_01	41 samples	-24.18 1.0e+00 (pic) (net)	-23.59 1.8e-04 (pic) (net)	-24.63 1.0e-00 (pic) (net) Clust=( 0.05 0.95 )	-23.75 3.3e-02 (pic) (net) Clust=( 0.05 0.95 )
#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
45	V$FOXO1_02	21 samples	-16.15 1.0e+00 (pic) (net)	-16.47 7.8e-01 (pic) (net)	-15.80 4.2e-02 (pic) (net) Clust=( 0.87 0.13 )	-16.56 7.5e-01 (pic) (net) Clust=( 0.83 0.17 )
46	V$FOXO4_01	30 samples	-12.99 1.0e+00 (pic) (net)	-12.99 1.0e+00 (pic) (net)	-12.96 4.4e-01 (pic) (net) Clust=( 0.70 0.30 )	-12.76 5.7e-02 (pic) (net) Clust=( 0.77 0.23 )
47	V$GATA6_01	69 samples	-13.76 1.0e+00 (pic) (net)	-13.76 1.0e+00 (pic) (net)	-13.92 9.2e-01 (pic) (net) Clust=( 0.83 0.17 )	-13.87 8.0e-01 (pic) (net) Clust=( 0.29 0.71 )
48	V$GKLF_01	49 samples	-20.56 1.0e+00 (pic) (net)	-20.32 9.6e-03 (pic) (net)	-20.70 8.3e-01 (pic) (net) Clust=( 0.63 0.37 )	-20.42 1.7e-01 (pic) (net) Clust=( 0.12 0.88 )
49	V$GNCF_01	37 samples	-10.51 1.0e+00 (pic) (net)	-10.63 9.2e-01 (pic) (net)	-10.25 1.3e-02 (pic) (net) Clust=( 0.06 0.94 )	-10.42 3.1e-01 (pic) (net) Clust=( 0.94 0.06 )
50	V$HAND1E47_01	29 samples	-23.22 1.0e+00 (pic) (net)	-23.11 3.0e-01 (pic) (net)	-23.31 6.2e-01 (pic) (net) Clust=( 0.59 0.41 )	-23.56 8.1e-01 (pic) (net) Clust=( 0.38 0.62 )
51	V$HNF1_01	26 samples	-17.89 1.0e+00 (pic) (net)	-17.98 8.2e-01 (pic) (net)	-17.97 6.6e-01 (pic) (net) Clust=( 0.75 0.25 )	-18.30 9.0e-01 (pic) (net) Clust=( 0.08 0.92 )
52	V$IRF1_01	21 samples	-15.55 1.0e+00 (pic) (net)	-15.35 4.1e-01 (pic) (net)	-14.68 3.2e-02 (pic) (net) Clust=( 0.67 0.33 )	-13.74 3.4e-02 (pic) (net) Clust=( 0.13 0.87 )
53	V$IRF7_01	28 samples	-30.82 1.0e+00 (pic) (net)	-29.52 1.0e-01 (pic) (net)	-27.56 1.7e-04 (pic) (net) Clust=( 0.29 0.71 )	-28.46 1.4e-02 (pic) (net) Clust=( 0.29 0.71 )
54	V$LHX3_01	40 samples	-7.36 1.0e+00 (pic) (net)	-7.43 7.8e-01 (pic) (net)	-7.14 2.7e-03 (pic) (net) Clust=( 0.90 0.10 )	-7.13 4.3e-02 (pic) (net) Clust=( 0.94 0.06 )
55	V$LUN1_01	24 samples	-10.46 1.0e+00 (pic) (net)	-7.87 1.6e-07 (pic) (net)	-9.52 3.4e-04 (pic) (net) Clust=( 0.19 0.81 )	-6.92 4.1e-09 (pic) (net) Clust=( 0.09 0.91 )
#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
56	V$MZF1_01	20 samples	-8.59 1.0e+00 (pic) (net)	-8.36 0.0e+00 (pic) (net)	-8.42 1.3e-01 (pic) (net) Clust=( 0.18 0.82 )	-8.61 5.3e-01 (pic) (net) Clust=( 0.90 0.10 )
57	V$NCX_01	40 samples	-16.22 1.0e+00 (pic) (net)	-16.22 1.0e+00 (pic) (net)	-16.28 6.5e-01 (pic) (net) Clust=( 0.28 0.72 )	-16.21 4.9e-01 (pic) (net) Clust=( 0.41 0.59 )
58	V$NFKAPPAB_01	40 samples	-7.78 1.0e+00 (pic) (net)	-7.73 2.2e-01 (pic) (net)	-7.67 9.5e-02 (pic) (net) Clust=( 0.06 0.94 )	-7.70 3.1e-01 (pic) (net) Clust=( 0.73 0.27 )
59	V$NKX22_01	23 samples	-10.70 1.0e+00 (pic) (net)	-9.38 5.0e-03 (pic) (net)	-9.08 1.8e-04 (pic) (net) Clust=( 0.23 0.77 )	-9.09 9.2e-04 (pic) (net) Clust=( 0.09 0.91 )
60	V$NRSF_01	28 samples	-15.76 1.0e+00 (pic) (net)	-15.60 3.8e-01 (pic) (net)	-15.07 3.5e-04 (pic) (net) Clust=( 0.76 0.24 )	-15.15 1.8e-01 (pic) (net) Clust=( 0.92 0.08 )
61	V$OCT1_01	56 samples	-18.97 1.0e+00 (pic) (net)	-18.92 1.5e-02 (pic) (net)	-18.94 3.8e-01 (pic) (net) Clust=( 0.66 0.34 )	-18.91 3.4e-01 (pic) (net) Clust=( 0.96 0.04 )
62	V$OCT1_02	44 samples	-18.08 1.0e+00 (pic) (net)	-18.08 1.0e+00 (pic) (net)	-18.39 9.8e-01 (pic) (net) Clust=( 0.65 0.35 )	-18.54 1.0e-00 (pic) (net) Clust=( 0.93 0.07 )
63	V$OCT1_03	51 samples	-17.18 1.0e+00 (pic) (net)	-17.18 4.2e-02 (pic) (net)	-17.25 6.6e-01 (pic) (net) Clust=( 0.50 0.50 )	-17.30 7.7e-01 (pic) (net) Clust=( 0.41 0.59 )
64	V$OCT1_04	47 samples	-30.85 1.0e+00 (pic) (net)	-30.94 8.9e-01 (pic) (net)	-31.33 9.9e-01 (pic) (net) Clust=( 0.44 0.56 )	-31.79 1.0e+00 (pic) (net) Clust=( 0.60 0.40 )
65	V$PAX2_01	32 samples	-29.92 1.0e+00 (pic) (net)	-30.03 8.8e-01 (pic) (net)	-30.07 6.4e-01 (pic) (net) Clust=( 0.53 0.47 )	-29.50 2.2e-01 (pic) (net) Clust=( 0.69 0.31 )
66	V$PAX2_02	37 samples	-12.64 1.0e+00 (pic) (net)	-12.64 1.0e+00 (pic) (net)	-12.78 8.0e-01 (pic) (net) Clust=( 0.49 0.51 )	-12.93 9.3e-01 (pic) (net) Clust=( 0.06 0.94 )
#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
67	V$PAX6_01	47 samples	-27.02 1.0e+00 (pic) (net)	-26.90 2.0e-01 (pic) (net)	-26.85 2.8e-01 (pic) (net) Clust=( 0.89 0.11 )	-27.19 6.6e-01 (pic) (net) Clust=( 0.56 0.44 )
68	V$PAX8_01	35 samples	-26.93 1.0e+00 (pic) (net)	-26.93 1.0e+00 (pic) (net)	-27.18 7.8e-01 (pic) (net) Clust=( 0.46 0.54 )	-26.97 5.4e-01 (pic) (net) Clust=( 0.25 0.75 )
69	V$PAX8_B	23 samples	-32.75 1.0e+00 (pic) (net)	-33.10 9.6e-01 (pic) (net)	-34.15 1.0e+00 (pic) (net) Clust=( 0.55 0.45 )	-34.45 1.0e-00 (pic) (net) Clust=( 0.45 0.55 )
70	V$PBX1_02	40 samples	-20.04 1.0e+00 (pic) (net)	-17.73 3.3e-03 (pic) (net)	-17.85 7.4e-05 (pic) (net) Clust=( 0.21 0.79 )	-17.18 4.0e-04 (pic) (net) Clust=( 0.21 0.79 )
71	V$PPARG_01	72 samples	-24.32 1.0e+00 (pic) (net)	-18.08 1.2e-07 (pic) (net)	-18.54 1.8e-08 (pic) (net) Clust=( 0.81 0.19 )	-17.45 1.2e-07 (pic) (net) Clust=( 0.81 0.19 )
72	V$PPARG_02	28 samples	-29.79 1.0e+00 (pic) (net)	-27.08 7.8e-03 (pic) (net)	-24.32 1.8e-05 (pic) (net) Clust=( 0.23 0.77 )	-24.53 2.2e-04 (pic) (net) Clust=( 0.77 0.23 )
73	V$RORA1_01	25 samples	-14.73 1.0e+00 (pic) (net)	-14.73 1.0e+00 (pic) (net)	-14.67 3.3e-01 (pic) (net) Clust=( 0.29 0.71 )	-14.35 4.1e-05 (pic) (net) Clust=( 0.92 0.08 )
74	V$RORA2_01	36 samples	-10.45 1.0e+00 (pic) (net)	-10.45 1.0e+00 (pic) (net)	-9.97 0.0e+00 (pic) (net) Clust=( 0.06 0.94 )	-9.94 0.0e+00 (pic) (net) Clust=( 0.26 0.74 )
75	V$RSRFC4_01	38 samples	-15.60 1.0e+00 (pic) (net)	-15.60 1.0e+00 (pic) (net)	-15.23 6.9e-06 (pic) (net) Clust=( 0.06 0.94 )	-15.23 6.5e-06 (pic) (net) Clust=( 0.25 0.75 )
76	V$RSRFC4_Q2	27 samples	-23.13 1.0e+00 (pic) (net)	-19.70 1.2e-05 (pic) (net)	-20.28 9.0e-06 (pic) (net) Clust=( 0.73 0.27 )	-19.60 4.9e-06 (pic) (net) Clust=( 0.71 0.29 )
77	V$R_01	35 samples	-26.84 1.0e+00 (pic) (net)	-27.03 8.9e-01 (pic) (net)	-27.03 8.5e-01 (pic) (net) Clust=( 0.09 0.91 )	-27.31 9.0e-01 (pic) (net) Clust=( 0.18 0.82 )
#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
78	V$S8_01	59 samples	-20.85 1.0e+00 (pic) (net)	-19.28 6.7e-05 (pic) (net)	-19.57 3.3e-06 (pic) (net) Clust=( 0.54 0.46 )	-19.63 1.4e-02 (pic) (net) Clust=( 0.37 0.63 )
79	V$SOX5_01	23 samples	-10.63 1.0e+00 (pic) (net)	-10.63 1.0e+00 (pic) (net)	-10.47 6.1e-02 (pic) (net) Clust=( 0.09 0.91 )	-10.48 7.7e-02 (pic) (net) Clust=( 0.15 0.85 )
80	V$SOX9_B1	73 samples	-17.84 1.0e+00 (pic) (net)	-17.66 4.2e-02 (pic) (net)	-17.47 1.9e-02 (pic) (net) Clust=( 0.29 0.71 )	-17.27 2.2e-03 (pic) (net) Clust=( 0.21 0.79 )
81	V$SPZ1_01	30 samples	-24.90 1.0e+00 (pic) (net)	-24.92 6.5e-01 (pic) (net)	-24.65 2.6e-01 (pic) (net) Clust=( 0.58 0.42 )	-25.20 8.1e-01 (pic) (net) Clust=( 0.56 0.44 )
82	V$SRY_01	23 samples	-8.59 1.0e+00 (pic) (net)	-8.59 1.0e+00 (pic) (net)	-8.65 7.6e-01 (pic) (net) Clust=( 0.87 0.13 )	-8.71 9.2e-01 (pic) (net) Clust=( 0.87 0.13 )
83	V$SRY_02	29 samples	-15.84 1.0e+00 (pic) (net)	-15.84 1.0e+00 (pic) (net)	-16.34 1.0e-00 (pic) (net) Clust=( 0.77 0.23 )	-16.16 9.8e-01 (pic) (net) Clust=( 0.71 0.29 )
84	V$STAT5A_01	33 samples	-20.69 1.0e+00 (pic) (net)	-19.39 1.7e-02 (pic) (net)	-18.71 4.3e-03 (pic) (net) Clust=( 0.80 0.20 )	-18.28 5.2e-03 (pic) (net) Clust=( 0.78 0.22 )
85	V$STAT5A_02	37 samples	-35.50 1.0e+00 (pic) (net)	-35.50 1.0e+00 (pic) (net)	-35.54 5.8e-01 (pic) (net) Clust=( 0.51 0.49 )	-36.12 1.0e-00 (pic) (net) Clust=( 0.56 0.44 )
86	V$STAT5B_01	46 samples	-18.36 1.0e+00 (pic) (net)	-17.13 1.1e-03 (pic) (net)	-16.33 1.5e-03 (pic) (net) Clust=( 0.13 0.87 )	-16.57 4.3e-03 (pic) (net) Clust=( 0.34 0.66 )
87	V$TBP_01	47 samples	-7.13 1.0e+00 (pic) (net)	-6.81 3.1e-02 (pic) (net)	-6.98 1.3e-02 (pic) (net) Clust=( 0.05 0.95 )	-6.49 2.4e-04 (pic) (net) Clust=( 0.95 0.05 )
88	V$VJUN_01	24 samples	-14.77 1.0e+00 (pic) (net)	-14.77 1.0e+00 (pic) (net)	-14.05 1.7e-09 (pic) (net) Clust=( 0.09 0.91 )	-13.92 8.3e-09 (pic) (net) Clust=( 0.09 0.91 )
#	NAME	DATA	PSSM (likelihood,pval)	Tree (likelihood,pval)	Mixture of PSSMs (likelihood,pval)	Mixture of Trees (likelihood,pval)
89	V$VMYB_01	24 samples	-12.48 1.0e+00 (pic) (net)	-13.01 8.7e-01 (pic) (net)	-12.32 3.3e-01 (pic) (net) Clust=( 0.67 0.33 )	-12.29 3.6e-01 (pic) (net) Clust=( 0.67 0.33 )
90	V$VMYB_02	29 samples	-8.62 1.0e+00 (pic) (net)	-8.62 1.0e+00 (pic) (net)	-8.33 4.3e-04 (pic) (net) Clust=( 0.07 0.93 )	-8.66 5.5e-01 (pic) (net) Clust=( 0.93 0.07 )
91	V$XBP1_01	33 samples	-22.71 1.0e+00 (pic) (net)	-22.87 9.0e-01 (pic) (net)	-22.84 7.1e-01 (pic) (net) Clust=( 0.59 0.41 )	-22.87 7.0e-01 (pic) (net) Clust=( 0.60 0.40 )
92	V$ZIC1_01	30 samples	-13.60 1.0e+00 (pic) (net)	-13.60 1.0e+00 (pic) (net)	-13.85 9.5e-01 (pic) (net) Clust=( 0.59 0.41 )	-13.89 9.8e-01 (pic) (net) Clust=( 0.41 0.59 )
93	V$ZIC2_01	30 samples	-13.66 1.0e+00 (pic) (net)	-13.66 1.0e+00 (pic) (net)	-14.06 1.0e-00 (pic) (net) Clust=( 0.57 0.43 )	-14.06 1.0e-00 (pic) (net) Clust=( 0.51 0.49 )
94	V$ZIC3_01	35 samples	-13.25 1.0e+00 (pic) (net)	-13.25 1.0e+00 (pic) (net)	-13.56 9.9e-01 (pic) (net) Clust=( 0.60 0.40 )	-13.44 9.4e-01 (pic) (net) Clust=( 0.84 0.16 )
95	V$ZID_01	35 samples	-13.31 1.0e+00 (pic) (net)	-13.57 9.5e-01 (pic) (net)	-13.09 4.2e-02 (pic) (net) Clust=( 0.50 0.50 )	-13.35 5.7e-01 (pic) (net) Clust=( 0.94 0.06 )